Gaming
Video driver
If you followed Installation/Useful packages/Graphics Driver your graphics driver & Vulkan should be already set-up correctly
Graphics card configuration tool
AMD
yay -S radeon-profile-git radeon-profile-daemon-git
systemctl enable --now radeon-profile-daemon
NVIDIA
yay -S nvidia-settings
Wine
Libraries
Recommended by Lutris
yay -S --needed wine-staging giflib lib32-giflib libpng lib32-libpng libldap lib32-libldap gnutls lib32-gnutls mpg123 lib32-mpg123 openal lib32-openal v4l-utils lib32-v4l-utils libpulse lib32-libpulse libgpg-error lib32-libgpg-error alsa-plugins lib32-alsa-plugins alsa-lib lib32-alsa-lib libjpeg-turbo lib32-libjpeg-turbo sqlite lib32-sqlite libxcomposite lib32-libxcomposite libxinerama lib32-libgcrypt libgcrypt lib32-libxinerama ncurses lib32-ncurses opencl-icd-loader lib32-opencl-icd-loader libxslt lib32-libxslt libva lib32-libva gtk3 lib32-gtk3 gst-plugins-base-libs lib32-gst-plugins-base-libs
Other packages not listed by Lutris
yay -S vkd3d lib32-vkd3d faudio lib32-faudio
Custom Wine/Proton
For custom Proton, I recommend GloriousEgroll's builds. For Steam and Lutris. These can be installed using ProtonUp-Qt
yay -S protonup-qt
For custom Wine, I recommend Tk-Glitch which can be downloaded from here and installed with unzip wine-tkg-build.zip && yay -U wine-tkg-*.pkg.tar.zst
Programs
Install basic gaming tools
yay -S lutris steam gamemode lib32-gamemode
Custom kernel
WARNING
If you are using NVIDIA and want to use a custom kernel you need to use nvidia-dkms since nvidia is just for the mainline linux kernel and nvidia-lts for linux-lts
yay -Rdd nvidia
yay -S nvidia-dkms
Alternatively you can use nvidia-all to get the latest NVIDIA driver for all kernels
Zen
yay -S linux-zen linux-zen-headers
Tk-Glitch
See linux-tkg
After installing
You need to re-generate your grub config
sudo grub-mkconfig -o /boot/grub/grub.cfg
Tweak Esync
If this command prints out a value which is equal or greater to 524288 you're all set
ulimit -Hn
However, if it doesn't, or you want to further improve it:
sudo nano /etc/systemd/system.conf
sudo nano /etc/systemd/user.conf
append this in both files
DefaultLimitNOFILE=1024:1048576
Source: https://github.com/zfigura/wine/blob/master/README.esync
Other tweaks
The Arch wiki has a page dedicated to Gaming with a few other tweaks you might want to look into.